Neural machine translation of clinical text: an empirical investigation into multilingual pre-trained language models and transfer-learning

Авторы

Ключевые слова:

Computer science, Machine translation, Artificial intelligence, Natural language processing, Terminology, Transfer of learning, Margin (machine learning), Language model

Аннотация

Clinical text and documents contain very rich information and knowledge in healthcare, and their processing using state-of-the-art language technology becomes very important for building intelligent systems for supporting healthcare and social good. This processing includes creating language understanding models and translating resources into other natural languages to share domain-specific cross-lingual knowledge. In this work, we conduct investigations on clinical text machine translation by examining multilingual neural network models using deep learning such as Transformer based structures. Furthermore, to address the language resource imbalance issue, we also carry out experiments using a transfer learning methodology based on massive multilingual pre-trained language models (MMPLMs). The experimental results on three sub-tasks including (1) clinical case (CC), (2) clinical terminology (CT), and (3) ontological concept (OC) show that our models achieved top-level performances in the ClinSpEn-2022 shared task on English-Spanish clinical domain data. Furthermore, our expert-based human evaluations demonstrate that the small-sized pre-trained language model (PLM) outperformed the other two extra-large language models by a large margin in the clinical domain fine-tuning, which finding was never reported in the field. Finally, the transfer learning method works well in our experimental setting using the WMT21fb model to accommodate a new language space Spanish that was not seen at the pre-training stage within WMT21fb itself, which deserves more exploitation for clinical knowledge transformation, e.g. to investigate into more languages. These research findings can shed some light on domain-specific machine translation development, especially in clinical and healthcare fields. Further research projects can be carried out based on our work to improve healthcare text analytics and knowledge transformation. Our data is openly available for research purposes at: https://github.com/HECTA-UoM/ClinicalNMT.

Источник и лицензия. Статья открытого доступа, впервые опубликована как «Neural machine translation of clinical text: an empirical investigation into multilingual pre-trained language models and transfer-learning» в журнале Frontiers in Digital Health, 2024. DOI: 10.3389/fdgth.2024.1211564. © Lifeng Han, Serge Gladkoff, Gleb Erofeev, Irina Sorokina, Betty Galiano, Goran Nenadić. Воспроизведена без изменений по лицензии Creative Commons Attribution 4.0.

Библиографические ссылки

Bodenreider, O. (2003). The Unified Medical Language System (UMLS): integrating biomedical terminology. Nucleic Acids Research. https://doi.org/10.1093/nar/gkh061

Donnelly, K. (2006). SNOMED-CT: The advanced terminology and coding system for eHealth.. PubMed.

Spasić, ., Nenadić, G. (2020). Clinical Text Data in Machine Learning: Systematic Review. JMIR Medical Informatics. https://doi.org/10.2196/17984

Henry, S., Buchan, K., Filannino, M. et al. (2019). 2018 n2c2 shared task on adverse drug events and medication extraction in electronic health records. Journal of the American Medical Informatics Association. https://doi.org/10.1093/jamia/ocz166

Dew, K., Turner, A., Choi, Y. et al. (2018). Development of machine translation technology for assisting health communication: A systematic review. Journal of Biomedical Informatics. https://doi.org/10.1016/j.jbi.2018.07.018

Kovačević, A., Dehghan, A., Filannino, M. et al. (2013). Combining rules and machine learning for extraction of temporal expressions and events from clinical narratives. Journal of the American Medical Informatics Association. https://doi.org/10.1136/amiajnl-2013-001625

Elbattah, M., Arnaud, É., Gignon, M. et al. (2021). The Role of Text Analytics in Healthcare: A Review of Recent Developments and Applications. https://doi.org/10.5220/0010414508250832

Oyebode, O., Ndulue, C., Adib, A. et al. (2021). Health, Psychosocial, and Social Issues Emanating From the COVID-19 Pandemic Based on Social Media Comments: Text Mining and Thematic Analysis Approach. JMIR Medical Informatics. https://doi.org/10.2196/22734

Опубликован

2026-08-22

Как цитировать

Neural machine translation of clinical text: an empirical investigation into multilingual pre-trained language models and transfer-learning. (2026). QAIRU Journal, 1(2). https://ojs.bbx.kz/journal/article/view/7